AMPK and Diabetes

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Diabetes is commonly known as the sugar disease. It happens when the body is unable to process sugar effectively. The primary cause of diabetes is having a high level of blood glucose — hyperglycemia. Your body’s inability to produce enough insulin to counteract the excess sugar leads to the condition.

In some cases, the body’s inability to utilize its insulin supply may also be to blame. There is also a possibility for diabetes to develop in a person whose immune system ends up attacking his or her pancreas. Insulin is developed by the pancreas.

Diabetes is a condition that people from different age groups experience. The thing about diabetes is that it can affect anyone especially those who have diabetes in their genes. There are other conditions that may contribute to it namely obesity, high blood pressure, high cholesterol, and even a lack of exercise.

There is no known cure available but there are medications that help manage the condition. Affecting millions around the world, there is a common prescription drug that is given to those with more severe cases of the disease; it is called Metformin. Metformin is used mostly by people who are afflicted with Type 2 diabetes. It is a chemical drug that helps bring down blood sugar levels.

Type 2 diabetes is a condition wherein there is a deficit in insulin production. This means that your pancreas is unable to create enough insulin for your body to manage your sugar consumption effectively.

AMPK is an enzyme that is found in the cells of the human body. AMPK means Adenosine Monophosphate-Activated Protein Kinase. It helps balance energy stores. Aside from aiding in weight loss by boosting your metabolism, it also helps promote longevity and has been found to combat diabetes quite effectively.

When the AMPK enzyme is successfully activated, it helps an individual lose weight. For those suffering from diabetes, proper weight management is crucial. With the help of the activated AMPK enzyme, they can expect their diet and exercise regimens to render improved results.

There are plenty of people who are unaware as to the relationship shared by AMPK and diabetes. The thing about AMPK is that for it to work, it requires activation and there have been countless studies that show that when activated, it can enhance the effects of Metformin. As a result, diabetics that take this drug can experience better treatment for their blood sugar levels over time.

Now, you might probably be wondering how Metformin and AMPK work together. As a diabetes sufferer takes in Metformin, the chemical drug activates the AMPK enzyme. As it is activated, the body turns on all energy generating components of your body and reduces energy consumption for some time. With a reduced consumption of energy comes a reduced level of fat and sugar stores as they are metabolized by the body.

Metformin is an excellent activator for this non-digestive enzyme and in turn, as the AMPK is activated, the effects of the drug is enhanced. Considering that the components that are used to make the Metformin are unnatural to the body, it requires sort of a kick for the body to absorb it thoroughly. This is where the AMPK plays an important role. And as for the AMPK, it is activated when the body experiences extreme change. This is satisfied by the introduction of the Metformin, a compound that the body is not used to.

As you know, the human body is not a perfect machine. It produces hormones and enzymes but not quite efficiently. In the same way, the necessary components like AMPK which requires activation are not activated the minute we are born. This is why there is a need for voluntary activation to take place.

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