Curcumin: An AMPK Activating Nutraceutical

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What is Curcumin?

Curcumin is a polyphenolic compound that is biologically active and has anti-inflammatory properties. It is a yellow colored chemical compound that is used as a food additive.

It is also processed to manufacture cosmetics, herbal supplements, food coloring, and as a food flavoring. This compound was isolated by chemists Pelletier and Vogel back in 1815.

They described it as a kind of yellow coloring matter. They were able to extract it form turmeric rhizomes and they called it as curcumin. Even though the west has yet to validate the potency of this polyphenol, it has been used for many centuries in Ayurvedic medicine.

Chemically, curcumin is classified as a type of natural phenol and it belongs to the curcuminoid group. It is responsible for the yellowish color of turmeric root.

What Plant(s) Is It Extracted From?

The active ingredient or compound that is found in turmeric is called curcumin. It can also be extracted from ginger but only in smaller amounts. It is the compound that gives turmeric its yellowish color.

Mechanism of AMPK Activation

According to studies, curcumin is an effective AMPK activator. Click here to see the review. It can also suppress the expression of gluconeogenic genes. Its potency to against inflammation and anti-oxidant properties have been acknowledged and documented.

Unfortunately curcumin’s mechanism of AMPK activation is currently unknown. What is known so far of its mechanism of action is rudimentary at best. Most of the trials so far can only confirm i