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    nthocyan sApigen"nBerber"eefimpouA isolAMethfromdS lrmon’scseal (Polygoes im sdArAMum)CurcumedEGCGGen"steedQtriceM"eA-Lipoich nidCryptoearshinoneApnle Cider VinegAr / PomeVATn/ao vinegAr /h nUTredanidArtp:gen"n fromdvancseedm of burdocka(Artp:um lapp-)AowrcialusBa"el="nBa nar Melre (CucurbiMane)Care-wineCinnamreCoQ10Creat,eeDarshen / Salvia Mile":rrhiza / TarshioneIIAExnrd-Vinst Oliog OilOmeVa-3 Fthtyh nidsFucoidAnGedseng/GlucosamineGynostemmAHydroxytyrosolNicot,ee (inLfthrcells)Pa.durat"n fromdBonsenbergia pa.durate (Ch"eese iencer)Red yeast rife (ankaflaved aA Lmreascin)ReishiRooibosViMamin E / gammA tocotriaqols + TurknyLtail / PSPwspan"old+jsos1m>Drugsheythr n":"AMe conwspan"old+jsoez-toc-sepe":"-endomw/h2> spirt : SalicylAMh di/>"Ily ttp://aos con. spirt decreases TGalevalm aA L=irculAM"ng fthtytonidm indobnse,heter-2 diabUTredpAM"aquo. Il enharchedfth-burnang dur"et eancfasM"et stpeenindheger yshumans,dwR-ih may an duWe areancdi/>"Ih mpape of aspirt oefvancon":"AM":" of cont

    Metformin: Metformin isdarbloo Lsugar-reduc"et ciUntt Many of its ant"-diabUTredfunpe":" Aaginnediaaom by con."Tanse includr stimulAM":" of fth-burnang aA Lglucose uptake, t they reduct":" indliogl glucose aA Lf@t /> duct":".

    Te azo},danediodms: Te drug on"sae-prely byL@n":"AM"nc PPAR, but"il olso"produces aAt"-diabUTredeffepes paroly byL@n":"AM"nc con. Il rapidly ttp://aos con t SEariousn/rssuee"cecludang liogl, fa0 /rssues, t thmuscs+. TZD aginvatoonly />cocribem for or.nroll"et bloo Lsugar, but"oause wh":10 gied aedarside-effepe.

    wspan"old+jsos1m> irmoacs / PAMhwaysheythr n":"AMe con ( advancliogl, fth, t thmuscs+)wspan"old+jsoez-toc-sepe":"-endomw/h2> Prd nael=ly any modulAMor vaat causWsdel=c:um ocfumulAM":" or Aco (deplel=daATP) can an":"AMe con.

    taponepe"n: taponepe"ntme"/> ducom by fthrcells. Il serves aedarsig al for stpr"AM":"."Dur"et fasM"et,r@taponepe"n stimulAMes"t thiecreases con, .coultiet "ntmnduchddfoo Lednake t threduchd ed rgy extr.diture. taponepe"ntlevaladrops after re/comiet;msimultaneously, Aconton":"ity dhceedme.

    Lepe"n: Lepe"n isfvancaAt"-obnsity t thsAM"aty hormoacrreleasethby fthrcells wthn c su.co me"/>nsent. Il max-Untscoogleat,et byLprx-Unt"et hypothalamic con fromdsupn.comang aw, m!--. Il does, howeogl, an":"AMe con indvancmuscs+st

    TeyroidhhormoacrT3: Te hormoacriecreases or.sumpt":n s acellulAr oxyged aA L="uses conton":"AM":" indvancmuscs+st

    ROS-/> duc"et ciUnts: ModulAMormheythrieduchavancgenerAM":" i.nrd ellulAr rnacl"vncoxyged spect N-wrif oxide

    wspan"old+jsos1m> irmoacs eythr n":"AMe Hypothalamic con wspan"old+jsoez-toc-sepe":"-endomw/h3> Cannab"eo,ds: Fou th h+Loannab"s plAnt,Loannab"eo,ds promoth Aconton":"ity wR-ih l"@ts ar acreasethaw, m!--. Howeogl, vanse fimpouA tenU oof tduce con indvancliogl aA Lf@t cells.

    Ganol"n: Te “huetry hormoac” me"/> ducom indvancstomach t thdisad> ged dur"et fasM"et. Il maednaeds normalcbloo Lglucose levalmat th frucS", for surviv", dur"et fasM"et or strifM calori .cowrifM":". Ganol"n stimulAMes"foo Lor.sumpt":n but"inhibiMsi con indvancliogl aA Lf@t /rssues, like cannab"eo,ds.

    Crrtisol

    irmoacs eythrIehibiM Hypothalamic conwspan"old+jsoez-toc-sepe":"-endomw/h3> Eowrcdiol

    Insu.co

    GLP-1

    Lepe"n

    Teyroidh irmoacs

    Ns in t Subsearchs eythrIehibiM Hypothalamic conw/p> Lipoich nid:rIehibiMs con indvanchypothalamus but"increases tt indvancliogl, fa0, t thmuscs+s.

    Nicot,ee: Wh":10 loss ceduchd by nicot,eeatsdecomed arey d na"AM":" of con advanchypothalamust

    QtriceM"e: Like lipoictonidvictciecreases con indvancliogl, fa0, t thmuscs+, t th nhibiMsictcindvanchypothalamust

    Ketodms: Ketodms agin,> ducom wthn vancbody edeers eancstpeenof keoosis;heythris, a stpeenindwR-ih vancbody burnedfth for fual,h nste-U s aglucose.

    wspan"old+jsos1m>Tech rel= Ieformat":"wspan"old+jsoez-toc-sepe":"-endomw/h2> conton"saasdan"up-streamh nhibiMPK s  mTOR

    contoan bn ttp://aom by Tak1, LKB1, or CaMKKβ

    contoan di/>"Ily ttp://ao eancfam ryrmUmb contblocke"vancmaed regulAMor s aSREBPcLlipogenesis

    contmay ttp://ao NRF2

    conton":"AM":" ofte" reoult Acefeancdecrease s  mTOR. Buthey recaginsome scenariosnindwR-ih bor conto thmTOR a Wettp://aod."> is btcausWe contdohednoof nhibiMimTOR di/>"Ily; rathervictciehibiMsi" /> teed eythrdi/>"Ily ttp://aos mTOR.

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